GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ddit3 | multiple interactions | EXP | | 6480464 | CTD | Sirolimus inhibits the reaction [arsenite results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 protein] | PMID:11145585 PMID:22215663 | Ddit3 | multiple interactions | ISO | Ddit3 (Rattus norvegicus) | 6480464 | CTD | Sirolimus inhibits the reaction [cadmium acetate results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [TSC2 gene mutant form results in increased expression of DDIT3 protein] | PMID:19420259 PMID:29870746 | Ddit3 | multiple interactions | ISO | DDIT3 (Homo sapiens) | 6480464 | CTD | [(+)-JQ1 compound co-treated with Sirolimus] affects the expression of DDIT3 mRNA; [Sirolimus results in decreased activity of MTOR protein] which results in decreased expression of DDIT3 protein; Sirolimus inhibits the reaction [arsenite results in increased expression of DDIT3 mRNA]; Sirolimus inhibits the reaction [arsenite results in increased expression of DDIT3 protein]; Sirolimus inhibits the reaction [honokiol results in increased expression of DDIT3 protein] | PMID:21321189 PMID:22215663 PMID:25307878 PMID:33550458 | | ||||||||||||||||||||||
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