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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621714
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sptan1
Name: spectrin, alpha, non-erythrocytic 1
Acc ID: CHEBI:3330
Term: Calpeptin
Definition: An amino acid amide that has formula C20H30N2O4.
Chemical ID: MESH:C071482
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sptan1multiple interactionsISOSptan1 (Mus musculus)6480464CTDcalpeptin inhibits the reaction [[lactacystin results in increased activity of CASP3 protein] which results in increased cleavage of SPTAN1 protein]; calpeptin inhibits the reaction [lactacystin results in increased cleavage of SPTAN1 protein]PMID:21683092
Sptan1multiple interactionsISOSPTAN1 (Homo sapiens)6480464CTDcalpeptin inhibits the reaction [dehydroeburicoic acid results in increased degradation of SPTAN1 protein]PMID:19848398
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