GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vcp | increases ubiquitination | ISO | VCP (Homo sapiens) | 6480464 | CTD | Arsenic results in increased ubiquitination of VCP protein | PMID:35994080 | Vcp | multiple interactions | ISO | VCP (Homo sapiens) | 6480464 | CTD | Arsenic promotes the reaction [VCP protein binds to PML protein]; ML-792 inhibits the reaction [Arsenic promotes the reaction [VCP protein binds to PML protein]]; RNF4 protein affects the reaction [Arsenic promotes the reaction [VCP protein binds to PML protein]]; TAK-243 inhibits the reaction [Arsenic promotes the reaction [VCP protein binds to PML protein]]; VCP protein affects the reaction [Arsenic results in increased degradation of PML protein] | PMID:36880596 | Vcp | multiple interactions | ISO | Vcp (Mus musculus) | 6480464 | CTD | [sodium arsenite results in increased abundance of Arsenic] which results in increased secretion of VCP protein | PMID:37527016 | | ||||||||||||||||||||||
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