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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621316
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:8024
Term: perindopril
Definition: An alpha-amino acid ester that is the ethyl ester of N-{(2S)-1-[(2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-yl]-1-oxopropan-2-yl}-L-norvaline
Chemical ID: MESH:D020913
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp2multiple interactionsEXP 6480464CTDPerindopril inhibits the reaction [Carbon Tetrachloride results in increased activity of MMP2 protein]PMID:12930639 PMID:14761280 PMID:16097048
Mmp2multiple interactionsISOMmp2 (Mus musculus)6480464CTDPerindopril inhibits the reaction [Diethylnitrosamine results in increased expression of MMP2 protein]PMID:29859236
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