GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp2 | decreases expression | EXP | | 6480464 | CTD | resveratrol results in decreased expression of MMP2 protein | PMID:25462211 | Mmp2 | multiple interactions | EXP | | 6480464 | CTD | [Dimethyl Sulfoxide co-treated with resveratrol] inhibits the reaction [Lipopolysaccharides results in increased expression of MMP2 protein]; Leuprolide inhibits the reaction [resveratrol results in decreased expression of MMP2 protein]; resveratrol inhibits the reaction [Leuprolide results in decreased expression of MMP2 protein]; resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of MMP2 protein] | PMID:25462211 PMID:26497626 | Mmp2 | affects secretion | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | resveratrol affects the secretion of MMP2 protein | PMID:24802182 | Mmp2 | decreases activity | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased activity of MMP2 protein | PMID:16317118 PMID:17935668 | Mmp2 | decreases expression | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | Resveratrol results in decreased expression of MMP2; Resveratrol results in decreased expression of MMP2 mRNA; Resveratrol results in decreased expression of MMP2 protein | PMID:16084059 PMID:17935668 PMID:21209944 PMID:21238464 PMID:23992306 PMID:24841706 PMID:25605016 PMID:27064016 | Mmp2 | decreases expression | ISO | Mmp2 (Mus musculus) | 6480464 | CTD | resveratrol results in decreased expression of MMP2 mRNA | PMID:25394648 | Mmp2 | decreases secretion | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased secretion of MMP2 protein | PMID:10733549 PMID:18674879 PMID:20677551 | Mmp2 | increases expression | ISO | Mmp2 (Mus musculus) | 6480464 | CTD | resveratrol results in increased expression of MMP2 protein | PMID:18572362 | Mmp2 | increases secretion | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | resveratrol results in increased secretion of MMP2 protein | PMID:22314268 | Mmp2 | multiple interactions | ISO | MMP2 (Homo sapiens) | 6480464 | CTD | [SU 1498 results in decreased activity of KDR protein] inhibits the reaction [resveratrol results in increased secretion of MMP2 protein]; MIR328 mRNA affects the reaction [resveratrol results in decreased expression of MMP2 protein]; pyrazolanthrone inhibits the reaction [resveratrol results in decreased expression of MMP2]; pyrazolanthrone promotes the reaction [resveratrol results in decreased expression of and results in decreased activity of MMP2 protein]; resveratrol affects the activity of and affects the secretion of MMP2 protein; resveratrol inhibits the reaction [7-ketocholesterol results in increased expression of MMP2 protein]; resveratrol inhibits the reaction [CREB1 protein binds to MMP2 promoter]; resveratrol inhibits the reaction [HMOX1 protein results in increased expression of MMP2 protein]; resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of MMP2 protein]; resveratrol inhibits the reaction [TGFB1 protein results in increased expression of MMP2 mRNA]; resveratrol inhibits the reaction [TGFB1 protein results in increased expression of MMP2 protein]; resveratrol inhibits the reaction [TNF protein results in increased activity of MMP2 protein]; resveratrol results in decreased expression of and results in decreased activity of MMP2 protein; SB 203580 promotes the reaction [resveratrol results in decreased expression of and results in decreased activity of MMP2 protein]; SB 203580 promotes the reaction [resveratrol results in decreased expression of MMP2] | PMID:17049120 PMID:18674879 PMID:20461740 PMID:22314268 PMID:23257246 PMID:23992306 PMID:24001813 PMID:24841706 PMID:24895526 PMID:25605016 PMID:25884904 PMID:26497626 | Mmp2 | multiple interactions | ISO | Mmp2 (Mus musculus) | 6480464 | CTD | Resveratrol inhibits the reaction [Calcium Chloride results in increased activity of MMP2 protein]; Resveratrol inhibits the reaction [Glucose results in increased activity of MMP2 protein] | PMID:21530968 PMID:24659233 | | ||||||||||||||||||||||
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