GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Txn1 | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of TXN1 protein | PMID:17178593 PMID:20453393 | Txn1 | multiple interactions | EXP | | 6480464 | CTD | 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Glucose results in decreased expression of TXN1 protein]; 8-bromocyclic GMP inhibits the reaction [Glucose results in decreased expression of TXN1 protein]; Dipyridamole inhibits the reaction [Glucose results in decreased expression of TXN1 protein]; KT 5823 inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in decreased expression of TXN1 protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Dipyridamole inhibits the reaction [Glucose results in decreased expression of TXN1 protein]] | PMID:20453393 | Txn1 | decreases expression | ISO | Txn1 (Mus musculus) | 6480464 | CTD | Glucose results in decreased expression of TXN1 protein | PMID:17178593 | Txn1 | increases secretion | ISO | TXN (Homo sapiens) | 6480464 | CTD | Glucose deficiency results in increased secretion of TXN protein | PMID:24802182 | Txn1 | multiple interactions | ISO | Txn1 (Mus musculus) | 6480464 | CTD | [[[[Glucose results in decreased expression of MIR17 mRNA] which results in increased expression of TXNIP mRNA] which results in increased expression of TXNIP protein] promotes the reaction [TXNIP protein binds to TXN1 protein]] which results in increased activity of MAP3K5 protein; [Glucose promotes the reaction [TXNIP protein binds to TXN1 protein]] which results in increased activity of MAP3K5 protein; Glucose promotes the reaction [TXNIP protein binds to TXN1 protein] | PMID:26660634 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |