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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621121
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdk6
Name: cyclin-dependent kinase 6
Acc ID: CHEBI:53509
Term: erlotinib hydrochloride
Definition: The hydrochloride salt of erlotinib.
Chemical ID: MESH:D000069347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdk6decreases expressionISOCDK6 (Homo sapiens)6480464CTDErlotinib Hydrochloride results in decreased expression of CDK6 proteinPMID:30136359
Cdk6multiple interactionsISOCDK6 (Homo sapiens)6480464CTDBetulinic Acid promotes the reaction [Erlotinib Hydrochloride results in decreased expression of CDK6 protein]PMID:30136359
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