GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Col1a1 | increases expression | EXP | | 6480464 | CTD | Nicotine results in increased expression of COL1A1 mRNA | PMID:33082140 | Col1a1 | multiple interactions | EXP | | 6480464 | CTD | [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COL1A1 mRNA; NGF protein affects the reaction [Nicotine results in increased expression of COL1A1 mRNA]; Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of COL1A1 mRNA]; Nicotine promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA]; Nicotine promotes the reaction [Carbon Tetrachloride results in increased expression of COL1A1 protein]; Nicotine promotes the reaction [Thioacetamide results in increased expression of COL1A1] | PMID:20230807 PMID:28440100 PMID:33082140 PMID:33640489 | Col1a1 | increases expression | ISO | Col1a1 (Rattus norvegicus) | 6480464 | CTD | Nicotine results in increased expression of COL1A1 mRNA; Nicotine results in increased expression of COL1A1 protein | PMID:34153408 | | ||||||||||||||||||||||
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