GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp7 | increases activity | ISO | CASP7 (Homo sapiens) | 6480464 | CTD | Amiodarone results in increased activity of CASP7 protein | PMID:23042730 PMID:23135547 | Casp7 | increases expression | ISO | Casp7 (Mus musculus) | 6480464 | CTD | Amiodarone results in increased expression of CASP7 mRNA | PMID:24489787 | Casp7 | multiple interactions | ISO | CASP7 (Homo sapiens) | 6480464 | CTD | alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein] | PMID:23042730 | |
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