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GENE - TERM ANNOTATION REPORT

RGD ID: 620722
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zfp36
Name: zinc finger protein 36
Acc ID: GO:0000165
Term: MAPK cascade
Definition: An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
Definition Source(s): PMID:20811974, PMID:9561267
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zfp36involved_inISOZFP36 (Homo sapiens)1624291RGD PMID:15187101

PMID:15187101
Zfp36involved_inISOZfp36 (Mus musculus)1624291RGD MGI:5784967 PMID:24733888 MGI:5795816 PMID:22844456

MGI:5784967 MGI:5795816 PMID:22844456 PMID:24733888
Zfp36involved_inISSUniProtKB:P228931600115UniProtGO_REF:0000024

GO_REF:0000024
Zfp36involved_inISSUniProtKB:P266511600115UniProtGO_REF:0000024

GO_REF:0000024
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