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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620631
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hrh4
Name: histamine receptor H4
Acc ID: CHEBI:74760
Term: 4-methylhistamine
Definition: An aralkylamino compound that is histamine bearing a methyl substituent at the 5 position on the ring.
Chemical ID: MESH:C025566
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hrh4multiple interactionsISOHRH4 (Homo sapiens)6480464CTD1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; 4-methylhistamine binds to and results in increased activity of HRH4 protein; [4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of CalciumPMID:17507084
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