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GENE - TERM ANNOTATION REPORT

RGD ID: 620621
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2a1
Name: BCL2-related protein A1
Acc ID: GO:0001836
Term: release of cytochrome c from mitochondria
Definition: The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.
Definition Source(s): GOC:add, GOC:mah, GOC:mtg_apoptosis, ISBN:0721639976, PMID:12925707, PMID:9560217
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2a1involved_inIBAMGI:1097161 or MGI:88138 or MGI:88139 or MGI:99702 or PANTHER:PTN000135648 or Bax (Rattus norvegicus) or Bak1 (Rattus norvegicus) or UniProtKB:Q07812 or UniProtKB:Q07817 or UniProtKB:Q16611 or UniProtKB:Q9UMX31600115GO_CentralGO_REF:0000033

GO_REF:0000033
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