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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620555
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt-nd1
Name: mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt-nd1decreases expressionISOMT-ND1 (Homo sapiens)6480464CTDCarbon Tetrachloride results in decreased expression of ND1 proteinPMID:35202708
Mt-nd1decreases expressionISOmt-Nd1 (Mus musculus)6480464CTDCarbon Tetrachloride results in decreased expression of ND1 proteinPMID:35202708
Mt-nd1multiple interactionsISOMT-ND1 (Homo sapiens)6480464CTDClorgyline inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; Clorgyline promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]]; MAOA protein affects the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; sarpogrelate promotes the reaction [Clorgyline inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]]PMID:35202708
Mt-nd1multiple interactionsISOmt-Nd1 (Mus musculus)6480464CTD[sarpogrelate co-treated with Carbidopa] inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; Carbidopa inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]; Carbidopa promotes the reaction [sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]]; sarpogrelate inhibits the reaction [Carbon Tetrachloride results in decreased expression of ND1 protein]PMID:35202708
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