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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620441
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl4
Name: C-C motif chemokine ligand 4
Acc ID: CHEBI:53001
Term: nickel sulfate
Definition: A metal sulfate having nickel(2+) as the metal ion.
Chemical ID: MESH:C029938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl4increases expressionISOCCL4 (Homo sapiens)6480464CTDnickel sulfate results in increased expression of CCL4 mRNA; nickel sulfate results in increased expression of CCL4 proteinPMID:12060402 PMID:15585374 PMID:16314067 PMID:16780908 PMID:18353026 PMID:20713136
Ccl4increases secretionISOCCL4 (Homo sapiens)6480464CTDnickel sulfate results in increased secretion of CCL4 proteinPMID:16314067
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