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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620299
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ereg
Name: epiregulin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eregdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of EREG mRNAPMID:24066056
Eregincreases expressionEXP 6480464CTDbisphenol A results in increased expression of EREG mRNAPMID:17010207 PMID:25181051
Eregincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of EREG genePMID:28505145
Eregdecreases expressionISOEREG (Homo sapiens)6480464CTDbisphenol A results in decreased expression of EREG mRNAPMID:29275510
Eregincreases methylationISOEREG (Homo sapiens)6480464CTDbisphenol A results in increased methylation of EREG genePMID:31601247
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