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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620299
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ereg
Name: epiregulin
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eregdecreases expressionEXP 6480464CTDEstradiol results in decreased expression of EREG mRNAPMID:23209616
Eregmultiple interactionsEXP 6480464CTDfulvestrant inhibits the reaction [Estradiol results in decreased expression of EREG mRNA]PMID:23209616
Eregincreases expressionISOEREG (Homo sapiens)6480464CTDEstradiol results in increased expression of EREG mRNAPMID:20106945 PMID:21632981
Eregmultiple interactionsISOEREG (Homo sapiens)6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of EREG mRNAPMID:30165855
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