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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620196
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp13
Name: matrix metallopeptidase 13
Acc ID: CHEBI:46680
Term: serpentine asbestos
Definition: null
Chemical ID: MESH:D017632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp13increases expressionISOMmp13 (Mus musculus)6480464CTDAsbestos, Serpentine results in increased expression of MMP13 mRNAPMID:16571779 PMID:23917077
Mmp13multiple interactionsISOMmp13 (Mus musculus)6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; rottlerin inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; RTKI cpd inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]PMID:16571779
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