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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619996
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bche
Name: butyrylcholinesterase
Acc ID: CHEBI:553827
Term: bambuterol
Definition: A carbamate ester that is terbutaline in which both of the phenolic hydroxy groups have been protected as the corresponding N,N-dimethylcarbamates. A long acting beta-adrenoceptor agonist used in the treatment of asthma, it is a prodrug for terbutaline.
Chemical ID: MESH:C047766
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bchedecreases activityISOBCHE (Homo sapiens)6480464CTDbambuterol results in decreased activity of BCHE proteinPMID:18582854
Bchedecreases activityISOBche (Mus musculus)6480464CTDbambuterol results in decreased activity of BCHE proteinPMID:15652380 PMID:18582854 PMID:18977317
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