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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619921
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rhoa
Name: ras homolog family member A
Acc ID: CHEBI:52288
Term: 1-octadec-9-enoylglycero-3-phosphate
Definition: A 2-lysophosphatidic acid that has formula C21H41O7P.
Chemical ID: MESH:C032881
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rhoaincreases activityEXP 6480464CTDlysophosphatidic acid results in increased activity of RHOA proteinPMID:15081308
Rhoaincreases activityISORHOA (Homo sapiens)6480464CTDlysophosphatidic acid results in increased activity of RHOA proteinPMID:24587105
Rhoamultiple interactionsISORHOA (Homo sapiens)6480464CTDFarnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]PMID:24587105
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