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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619871
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gclm
Name: glutamate cysteine ligase, modifier subunit
Acc ID: CHEBI:50866
Term: 3H-1,2-dithiole-3-thione
Definition: A 1,2-dithiole that has formula C3H2S3.
Chemical ID: MESH:C049325
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gclmaffects expressionEXP 6480464CTD1,2-dithiol-3-thione affects the expression of GCLM mRNAPMID:19162173
Gclmmultiple interactionsISOGclm (Mus musculus)6480464CTD[1,2-dithiol-3-thione results in increased activity of NFE2L2 protein] which results in increased expression of GCLM mRNAPMID:22495766
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