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GENE - TERM ANNOTATION REPORT

RGD ID: 619714
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rpa2
Name: replication protein A2
Acc ID: GO:0006289
Term: nucleotide-excision repair
Definition: A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
Definition Source(s): PMID:10197977
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rpa2involved_inISORPA2 (Homo sapiens)1624291RGD PMID:9430682

PMID:9430682
Rpa2involved_inIBAPANTHER:PTN000360435 or SGD:S000005256 or UniProtKB:P15927 or UniProtKB:Q131561600115GO_CentralGO_REF:0000033

GO_REF:0000033
Rpa2involved_inIEAPANTHER:PTHR13989:SF161600115TreeGrafterGO_REF:0000118

GO_REF:0000118
Rpa2involved_inISSUniProtKB:P159271600115UniProtGO_REF:0000024

GO_REF:0000024
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