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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61936
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a2
Name: solute carrier family 22 member 2
Acc ID: CHEBI:17833
Term: gentamycin
Definition: Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp.
Chemical ID: MESH:D005839
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a2affects expressionEXP 6480464CTDGentamicins affects the expression of SLC22A2 mRNAPMID:22005293
Slc22a2decreases expressionEXP 6480464CTDGentamicins results in decreased expression of SLC22A2 mRNA; Gentamicins results in decreased expression of SLC22A2 proteinPMID:22061828 PMID:29460972
Slc22a2increases transportISOSLC22A2 (Homo sapiens)6480464CTDSLC22A2 protein results in increased transport of GentamicinsPMID:27401566
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