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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61808
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Faah
Name: fatty acid amide hydrolase
Acc ID: CHEBI:9144
Term: silibinin
Definition: A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities.
Chemical ID: MESH:C440975
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Faahdecreases activityEXP 6480464CTDSilybin results in decreased activity of FAAH proteinPMID:37245739
Faahmultiple interactionsEXP 6480464CTDSilybin inhibits the reaction [FAAH protein results in increased metabolism of and results in decreased activity of anandamide]PMID:37245739
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