GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vdr | increases expression | EXP | | 6480464 | CTD | Vitamin D deficiency results in increased expression of VDR protein | PMID:9525346 | Vdr | increases activity | ISO | VDR (Homo sapiens) | 6480464 | CTD | Vitamin D analog results in increased activity of VDR protein | PMID:16280049 | Vdr | increases expression | ISO | Vdr (Mus musculus) | 6480464 | CTD | Vitamin D results in increased expression of VDR protein | PMID:30698894 | Vdr | increases expression | ISO | VDR (Homo sapiens) | 6480464 | CTD | Vitamin D results in increased expression of VDR mRNA; Vitamin D results in increased expression of VDR protein | PMID:30698894 PMID:33309619 | Vdr | multiple interactions | ISO | Vdr (Mus musculus) | 6480464 | CTD | [Particulate Matter co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D] results in increased expression of VDR protein | PMID:30698894 | Vdr | multiple interactions | ISO | VDR (Homo sapiens) | 6480464 | CTD | [bafilomycin A1 co-treated with Vitamin D] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D co-treated with bafilomycin A1] results in increased expression of VDR protein; [Silicon Dioxide co-treated with Vitamin D] results in increased expression of VDR protein; [TGFB1 protein co-treated with Vitamin D] results in increased expression of VDR mRNA; [Vitamin D co-treated with bisphenol A co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of VDR protein; Ketoconazole inhibits the reaction [Vitamin D analog results in increased activity of VDR protein]; Vitamin D analog inhibits the reaction [VDR protein binds to CYP24A1 promoter]; Vitamin D analog inhibits the reaction [VDR protein binds to NCOR2 protein]; Vitamin D analog promotes the reaction [[NCOR2 protein binds to VDR protein] which binds to CYP24A1 promoter]; Vitamin D analog promotes the reaction [VDR protein binds to NCOA1 protein]; Vitamin D analog promotes the reaction [VDR protein binds to RXRA protein]; Vitamin D binds to and affects the activity of VDR protein | PMID:16280049 PMID:21917910 PMID:30698894 PMID:33309619 PMID:33836827 | | ||||||||||||||||||||||
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