GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Vcam1 | decreases expression | ISO | Vcam1 (Mus musculus) | 6480464 | CTD | pirinixic acid results in decreased expression of VCAM1 mRNA; pirinixic acid results in decreased expression of VCAM1 protein | PMID:20131406 PMID:20813756 | Vcam1 | increases expression | ISO | Vcam1 (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased expression of VCAM1 mRNA | PMID:18445702 PMID:23811191 | Vcam1 | multiple interactions | ISO | Vcam1 (Mus musculus) | 6480464 | CTD | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of VCAM1 mRNA; pirinixic acid inhibits the reaction [Cisplatin results in increased expression of VCAM1 mRNA]; pirinixic acid inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 mRNA] | PMID:15814532 PMID:19710929 PMID:21300114 | Vcam1 | multiple interactions | ISO | VCAM1 (Homo sapiens) | 6480464 | CTD | pirinixic acid inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; pirinixic acid inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] | PMID:19693652 | | ||||||||||||||||||||||
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