GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tshb | multiple interactions | EXP | | 6480464 | CTD | [diisopropanolnitrosamine co-treated with Potassium Iodide] results in increased expression of TSHB protein; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with FOXE1 protein] binds to TPO promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to SLC5A5 enhancer; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TG promoter; [Potassium Iodide co-treated with TSHB protein co-treated with NKX2-1 protein] binds to TPO promoter; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 enhancer]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to SLC5A5 promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TG promoter]]; Potassium Iodide inhibits the reaction [TSHB protein promotes the reaction [PAX8 protein binds to TPO promoter]]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of DUOX2 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of FOXE1 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of NKX2-1 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of PAX8 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of SLC5A5 protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TG protein]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO mRNA]; Potassium Iodide inhibits the reaction [TSHB protein results in increased expression of TPO protein] | PMID:27568464 PMID:29050248 | | ||||||||||||||||||||||
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