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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3770
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Star
Name: steroidogenic acute regulatory protein
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stardecreases expressionEXP 6480464CTDlead acetate results in decreased expression of STAR mRNA; lead acetate results in decreased expression of STAR proteinPMID:25981801 PMID:26558472
Stardecreases expressionISOStar (Mus musculus)6480464CTDlead acetate results in decreased expression of STAR mRNA; lead acetate results in decreased expression of STAR proteinPMID:12647776 PMID:22806249 PMID:36088639
Starmultiple interactionsISOStar (Mus musculus)6480464CTD[lead acetate results in increased abundance of Lead] which results in decreased expression of STAR mRNA; Glycine inhibits the reaction [lead acetate results in decreased expression of STAR mRNA]; lead acetate inhibits the reaction [Bucladesine results in increased expression of STAR protein]; Taurine inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of STAR mRNA]PMID:11213355 PMID:36088639 PMID:36484981
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