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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3735
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sox10
Name: SRY-box transcription factor 10
Acc ID: CHEBI:39260
Term: pyriproxyfen
Definition: An aromatic ether that consists of propylene glycol having a 2-pyridyl group at the O-1 position and a 4-phenoxyphenyl group at the O-3 position.
Chemical ID: MESH:C055613
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sox10decreases expressionISOSox10 (Mus musculus)6480464CTDpyriproxyfen metabolite results in decreased expression of SOX10 mRNAPMID:34289950
Sox10multiple interactionsISOSox10 (Mus musculus)6480464CTD[pyriproxyfen metabolite co-treated with Triiodothyronine] results in decreased expression of SOX10 mRNAPMID:34289950
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