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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3705
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc2a2
Name: solute carrier family 2 member 2
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc2a2affects methylationISOSLC2A2 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of SLC2A2 promoterPMID:27901495
Slc2a2decreases expressionISOSlc2a2 (Mus musculus)6480464CTDBenzo(a)pyrene results in decreased expression of SLC2A2 mRNAPMID:19770486
Slc2a2decreases expressionISOSLC2A2 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of SLC2A2 mRNAPMID:20106945 PMID:21632981 PMID:22316170 PMID:26238291 PMID:32234424
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