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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3535
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rarb
Name: retinoic acid receptor, beta
Acc ID: CHEBI:63795
Term: all-trans-4-hydroxyretinoic acid
Definition: A retinoid that consists of all-trans-retinoic acid bearing a hydroxy substituent at position 4 on the cyclohexenyl ring.
Chemical ID: MESH:C019429
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rarbincreases activityISORARB (Homo sapiens)6480464CTD4-hydroxyretinoic acid results in increased activity of RARB proteinPMID:25492813
Rarbincreases expressionISORARB (Homo sapiens)6480464CTD4-hydroxyretinoic acid results in increased expression of RARB mRNAPMID:25492813
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