GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rarb | decreases expression | ISO | RARB (Homo sapiens) | 6480464 | CTD | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RARB mRNA | PMID:20426865 | Rarb | increases methylation | ISO | RARB (Homo sapiens) | 6480464 | CTD | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased methylation of RARB promoter | PMID:20426865 | Rarb | multiple interactions | ISO | RARB (Homo sapiens) | 6480464 | CTD | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide promotes the reaction [DNMT3A protein binds to RARB promoter] | PMID:20426865 | | ||||||||||||||||||||||
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