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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3054
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mbp
Name: myelin basic protein
Acc ID: CHEBI:6456
Term: lidocaine
Definition: The monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Chemical ID: MESH:D008012
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mbpdecreases expressionEXP 6480464CTDLidocaine results in decreased expression of MBP mRNA; Lidocaine results in decreased expression of MBP proteinPMID:33166664
Mbpmultiple interactionsEXP 6480464CTD[Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MBP mRNA]; [Antagomirs results in decreased expression of MIR199A2 mRNA] inhibits the reaction [Lidocaine results in decreased expression of MBP protein]PMID:33166664
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