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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3017
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lpl
Name: lipoprotein lipase
Acc ID: CHEBI:61159
Term: conjugated linoleic acid
Definition: An octadecadienoic acid having a system of two conjugated double bonds at any position.
Chemical ID: MESH:D044243
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lpldecreases expressionISOLpl (Mus musculus)6480464CTDLinoleic Acids, Conjugated results in decreased expression of LPL mRNAPMID:17322064
Lplincreases activityISOLPL (Homo sapiens)6480464CTDLinoleic Acids, Conjugated results in increased activity of LPL proteinPMID:23073171
Lplmultiple interactionsISOLpl (Mus musculus)6480464CTDrosiglitazone inhibits the reaction [Linoleic Acids, Conjugated results in decreased expression of LPL mRNA]PMID:17322064
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