GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Lhcgr | affects response to substance | ISO | Lhcgr (Mus musculus) | 6480464 | CTD | LHCGR affects the susceptibility to Testosterone | PMID:20164437 | Lhcgr | increases abundance | ISO | Lhcgr (Mus musculus) | 6480464 | CTD | LHCGR protein results in increased abundance of Testosterone | PMID:15514086 | Lhcgr | multiple interactions | ISO | Lhcgr (Mus musculus) | 6480464 | CTD | [FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA; [Leuprolide co-treated with Testosterone] results in decreased expression of LHCGR mRNA; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] | PMID:16032706 PMID:22285649 | Lhcgr | multiple interactions | ISO | LHCGR (Homo sapiens) | 6480464 | CTD | [FSHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA | PMID:18535249 | |
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