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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2845
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Htr1a
Name: 5-hydroxytryptamine receptor 1A
Acc ID: CHEBI:27928
Term: parathion
Definition: An organothiophosphate insecticide that has formula C10H14NO5PS.
Chemical ID: MESH:D010278
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Htr1aaffects expressionEXP 6480464CTDParathion affects the expression of HTR1A proteinPMID:18773955
Htr1adecreases expressionEXP 6480464CTDParathion results in decreased expression of HTR1A proteinPMID:17035140 PMID:19616088
Htr1aincreases expressionEXP 6480464CTDParathion results in increased expression of HTR1A proteinPMID:19616088
Htr1amultiple interactionsEXP 6480464CTDParathion inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein]PMID:17035140
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