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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2645
Species: Rattus norvegicus
RGD Object: Gene
Symbol: G6pd
Name: glucose-6-phosphate dehydrogenase
Acc ID: CHEBI:53001
Term: nickel sulfate
Definition: A metal sulfate having nickel(2+) as the metal ion.
Chemical ID: MESH:C029938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
G6pddecreases activityEXP 6480464CTDnickel sulfate results in decreased activity of G6PD proteinPMID:20950607
G6pdmultiple interactionsEXP 6480464CTDnaringin inhibits the reaction [nickel sulfate results in decreased activity of G6PD protein]PMID:20950607
G6pdincreases expressionISOG6PD (Homo sapiens)6480464CTDnickel sulfate results in increased expression of G6PD mRNAPMID:20566472
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