GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Fgf2 | decreases expression | EXP | | 6480464 | CTD | Tretinoin results in decreased expression of FGF2 mRNA | PMID:20488242 | Fgf2 | decreases response to substance | EXP | | 6480464 | CTD | Tretinoin results in decreased susceptibility to FGF2 protein | PMID:11675954 | Fgf2 | multiple interactions | EXP | | 6480464 | CTD | Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CCND3 mRNA]; Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CCNE1 mRNA]; Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CDK2 mRNA]; Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CDK4 mRNA]; Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CDK6 mRNA] | PMID:11675954 | Fgf2 | decreases expression | ISO | FGF2 (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased expression of FGF2 mRNA | PMID:21934132 | Fgf2 | decreases response to substance | ISO | Fgf2 (Mus musculus) | 6480464 | CTD | FGF2 protein results in decreased susceptibility to Tretinoin | PMID:16009726 | Fgf2 | multiple interactions | ISO | Fgf2 (Mus musculus) | 6480464 | CTD | FGF2 protein promotes the reaction [Tretinoin results in increased expression of GAB2 protein]; FGF2 protein promotes the reaction [Tretinoin results in increased expression of TUBB3 protein]; GAB2 protein promotes the reaction [FGF2 protein results in decreased susceptibility to Tretinoin] | PMID:16009726 | |
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