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GENE - TERM ANNOTATION REPORT

RGD ID: 2454
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11b2
Name: cytochrome P450, family 11, subfamily b, polypeptide 2
Acc ID: GO:0034651
Term: cortisol biosynthetic process
Definition: The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
Definition Source(s): GOC:BHF, GOC:mah, GOC:rl
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11b2involved_inISOCYP11B1 (Homo sapiens)1624291RGD PMID:19342457 PMID:2022736 PMID:8506298

PMID:19342457 PMID:2022736 PMID:8506298
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