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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2454
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11b2
Name: cytochrome P450, family 11, subfamily b, polypeptide 2
Acc ID: CHEBI:89455
Term: 18-hydroxycortisol
Definition: A 18-hydroxy steroid that is cortisol carrying a hydroxy group at position 18. Its urinary excretion is increased in patients with aldosterone-producing adenoma.
Chemical ID: MESH:C033689
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11b2affects chemical synthesisISOCYP11B1 (Homo sapiens)6480464CTDCYP11B1 protein affects the chemical synthesis of 18-hydroxycortisolPMID:15356073
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