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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2396
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cpt1a
Name: carnitine palmitoyltransferase 1A
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cpt1aaffects expressionEXP 6480464CTDperfluorooctanoic acid affects the expression of CPT1A mRNAPMID:17383973
Cpt1aincreases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of CPT1A mRNAPMID:19162173 PMID:28511854
Cpt1amultiple interactionsEXP 6480464CTD[Zeranol co-treated with perfluorooctanoic acid] results in increased expression of CPT1A mRNAPMID:35163327
Cpt1aaffects expressionISOCpt1a (Mus musculus)6480464CTDperfluorooctanoic acid affects the expression of CPT1A mRNAPMID:19429403
Cpt1aaffects expressionISOCPT1A (Homo sapiens)6480464CTDperfluorooctanoic acid affects the expression of CPT1A mRNAPMID:23567314
Cpt1adecreases expressionISOCpt1a (Mus musculus)6480464CTDperfluorooctanoic acid results in decreased expression of CPT1A mRNAPMID:21712084 PMID:30508572
Cpt1aincreases expressionISOCpt1a (Mus musculus)6480464CTDperfluorooctanoic acid results in increased expression of CPT1A mRNAPMID:17681415 PMID:25092180 PMID:26942110 PMID:30711707
Cpt1aincreases expressionISOCPT1A (Homo sapiens)6480464CTDperfluorooctanoic acid results in increased expression of CPT1A mRNAPMID:23978341 PMID:25868421 PMID:27153767 PMID:31676336 PMID:32588087 PMID:36326898 PMID:37302725 PMID:37738295
Cpt1amultiple interactionsISOCpt1a (Mus musculus)6480464CTDDietary Fats promotes the reaction [perfluorooctanoic acid results in increased expression of CPT1A mRNA]PMID:30711707
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