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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2282
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Runx2
Name: RUNX family transcription factor 2
Acc ID: CHEBI:17407
Term: 2-trans,6-trans-farnesyl diphosphate
Definition: The trans,trans-stereoisomer of farnesyl diphosphate.
Chemical ID: MESH:C004808
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Runx2multiple interactionsISORunx2 (Mus musculus)6480464CTDfarnesyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TNF protein inhibits the reaction [BMP2 results in increased expression of RUNX2 mRNA]]]PMID:18310456
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