GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | multiple interactions | EXP | | 6480464 | CTD | fisetin inhibits the reaction [Arsenic results in increased expression of CASP3 mRNA]; fisetin inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein] | PMID:25184746 PMID:36813806 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | fisetin results in increased activity of CASP3 protein | PMID:21964635 PMID:28181380 | Casp3 | increases cleavage | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | fisetin results in increased cleavage of CASP3 protein | PMID:31044527 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | fisetin inhibits the reaction [Lead results in increased cleavage of CASP3 protein] | PMID:31539617 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [fisetin results in increased activity of CASP3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [fisetin results in increased activity of CASP3 protein]; [Cisplatin co-treated with fisetin] results in increased cleavage of and results in increased activity of CASP3 protein; [fisetin co-treated with Paclitaxel] results in increased expression of CASP3 mRNA; [U 0126 co-treated with pyrazolanthrone] inhibits the reaction [fisetin results in increased cleavage of CASP3 protein]; [XMU-MP-1 co-treated with U 0126 co-treated with pyrazolanthrone] inhibits the reaction [fisetin results in increased cleavage of CASP3 protein]; fisetin inhibits the reaction [Silicon Dioxide results in increased expression of CASP3 mRNA]; pyrazolanthrone inhibits the reaction [fisetin results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [fisetin results in increased cleavage of CASP3 protein]; XMU-MP-1 inhibits the reaction [fisetin results in increased cleavage of CASP3 protein] | PMID:21216935 PMID:21964635 PMID:22931364 PMID:26884726 PMID:28181380 PMID:31044527 | | ||||||||||||||||||||||
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