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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:208185
Term: Ganoderic acid T
Definition: null
Chemical ID: MESH:C550530
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases activityISOCASP3 (Homo sapiens)6480464CTDganoderic acid T analog results in increased activity of CASP3 protein; ganoderic acid T results in increased activity of CASP3 proteinPMID:26282491
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [ganoderic acid T analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [ganoderic acid T analog results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [ganoderic acid T results in increased activity of CASP3 protein]; diphenyleneiodonium inhibits the reaction [ganoderic acid T analog results in increased activity of CASP3 protein]; diphenyleneiodonium inhibits the reaction [ganoderic acid T results in increased activity of CASP3 protein]PMID:26282491
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