GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | multiple interactions | EXP | | 6480464 | CTD | Silybin inhibits the reaction [Fluorouracil results in increased expression of CASP3 protein] | PMID:37335224 | Casp3 | increases activity | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Silybin results in increased activity of CASP3 protein | PMID:21969006 | Casp3 | increases expression | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Silybin results in increased expression of CASP3 mRNA | PMID:21969006 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide promotes the reaction [Silybin results in increased activity of CASP3 protein]; benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP3 protein]; Caffeine inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP3 protein]; pifithrin inhibits the reaction [Silybin results in increased cleavage of and results in increased activity of CASP3 protein]; Silybin inhibits the reaction [Acetaldehyde results in increased cleavage of CASP3 protein]; Silybin inhibits the reaction [Ethanol results in increased cleavage of CASP3 protein]; Silybin promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; Silybin results in increased cleavage of and results in increased activity of CASP3 protein | PMID:16777994 PMID:21969006 PMID:35158046 | | ||||||||||||||||||||||
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