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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:50277
Term: farnesyl diphosphate
Definition: A farnesyl phosphate that has formula C15H28O7P2.
Chemical ID: MESH:C004808
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTDfarnesyl pyrophosphate inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]PMID:15200425
Casp3multiple interactionsISOCASP3 (Homo sapiens)6480464CTDfarnesyl pyrophosphate inhibits the reaction [Lovastatin results in increased activity of and results in increased cleavage of CASP3 protein]PMID:18766339
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