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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2241
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Car3
Name: carbonic anhydrase 3
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Car3decreases expressionEXP 6480464CTDperfluorooctanoic acid results in decreased expression of CA3 mRNA; perfluorooctanoic acid results in decreased expression of CAR3 mRNA; perfluorooctanoic acid results in decreased expression of CAR3 proteinPMID:16221955 PMID:19162173 PMID:34958885
Car3decreases expressionISOCar3 (Mus musculus)6480464CTDperfluorooctanoic acid results in decreased expression of CAR3 proteinPMID:28126411
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