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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:31709
Term: iohexol
Definition: A benzenedicarboxamide compound having N-(2,3-dihydroxypropyl)carbamoyl groups at the 1- and 3-positions, iodo substituents at the 2-, 4- and 6-positions and an N-(2,3-dihydroxypropyl)acetamido group at the 5-position.
Chemical ID: MESH:D007472
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDIohexol results in decreased expression of BCL2 proteinPMID:36207783
Bcl2multiple interactionsEXP 6480464CTDAmlodipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]; cilnidipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]; Nifedipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]PMID:36207783
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDIohexol results in decreased expression of BCL2 proteinPMID:36207783
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTDAmlodipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]; cilnidipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]; Nifedipine inhibits the reaction [Iohexol results in decreased expression of BCL2 protein]PMID:36207783
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