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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:15727
Term: carnosine
Definition: A dipeptide that is the N-(beta-alanyl) derivative of L-histidine.
Chemical ID: MESH:D002336
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2multiple interactionsEXP 6480464CTDCarnosine inhibits the reaction [Sodium Nitrite results in decreased expression of BCL2 protein]PMID:28266762
Bcl2multiple interactionsISOBCL2 (Homo sapiens)6480464CTDasiatic acid promotes the reaction [Carnosine inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]]; Carnosine inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Glucose results in decreased expression of BCL2 mRNA]]PMID:30802477
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