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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:78665
Term: royal jelly
Definition: A mixture secreted by the hypopharyngeal gland of young worker bees (Apis mellifera) and fed as it is secreted to the queen bee and to larvae that are being raised as potential queen bees; it is not stored. Water makes up about two thirds of fresh royal jelly, with the remainder consisting mostly of proteins and sugars, followed by lipids (mostly free fatty acids containing short (8 to 10 carbon atom) chains with uncommon structures) and water-soluble vitamins.
Chemical ID: MESH:C058787
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2multiple interactionsEXP 6480464CTDroyal jelly inhibits the reaction [Fluorides results in increased expression of BCL2 protein]PMID:34227456
Bcl2multiple interactionsISOBcl2 (Mus musculus)6480464CTDroyal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA]PMID:30896085
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