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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2175
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp2a3
Name: ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp2a3multiple interactionsISOAtp2a3 (Mus musculus)6480464CTD[Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNAPMID:29935216
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